Survival of Node-negative Breast Cancer Patients Treated at the University Medical Centre Maribor in the Period 2000–2009
Identifieur interne : 000142 ( Main/Exploration ); précédent : 000141; suivant : 000143Survival of Node-negative Breast Cancer Patients Treated at the University Medical Centre Maribor in the Period 2000–2009
Auteurs : Nina Fokter Dovnik [Slovénie] ; Darja Arko [Slovénie] ; Nina As Sikošek [Slovénie] ; Iztok Taka [Slovénie]Source :
- Slovenian Journal of Public Health [ 0351-0026 ] ; 2017.
Abstract
Breast cancer is increasingly diagnosed in the early stages without regional nodal involvement. The aim of the present study was to determine the 5-year overall (OS) and breast cancer specific survival (BCSS) for patients with node-negative breast cancer treated at the University Medical Centre Maribor, and compare it with survival at the national level.
Medical records were searched for information on patients with lymph node-negative invasive breast cancer who received primary treatment at the University Medical Centre Maribor in the period 2000–2009. Information on all Slovenian node-negative breast cancer patients diagnosed in the same period was obtained from the Cancer Registry of Republic of Slovenia. Time trends in survival were assessed by comparing the periods 2000–2004 and 2005–2009.
The 5-year OS and BCSS of patients treated in Maribor in the period 2000–2009 were 92.3% (95% CI, 90.5%– 94.1%) and 96.4% (95% CI, 95.2%–97.6%), respectively, and did not differ from the corresponding OS and BCSS for Slovenian patients. Although the improvement in OS for patients from Maribor diagnosed in the period 2005–2009 compared to 2000–2004 did not reach statistical significance (HR 0.73; 95% CI, 0.51–1.05; p=0.086), BCSS significantly improved over the same time periods (HR 0.53; 95% CI, 0.30–0.94; p=0.028).
Survival of node-negative breast cancer patients treated at the University Medical Centre Maribor is comparable to survival of corresponding patients at the national level. The rising number of long-term breast cancer survivors places additional importance on survivorship care.
Url:
DOI: 10.1515/sjph-2017-0025
PubMed: 28713448
PubMed Central: 5504545
Affiliations:
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Oncology</institution>,<addr-line>Ljubljanska 5, 2000</addr-line><city>Maribor</city>,<country country="SI">Slovenia</country></nlm:aff><country xml:lang="fr">Slovénie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Arko, Darja" sort="Arko, Darja" uniqKey="Arko D" first="Darja" last="Arko">Darja Arko</name><affiliation wicri:level="1"><nlm:aff id="j_sjph-2017-0025_aff_002"><institution content-type="university">University Medical Centre Maribor</institution>,<institution content-type="university">University Clinical Department of Gynaecology and Perinatology</institution>,<addr-line>Ljubljanska 5, 2000</addr-line><city>Maribor</city><country country="SI">Slovenia</country></nlm:aff><country xml:lang="fr">Slovénie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey=" As Sikosek, Nina" sort=" As Sikosek, Nina" uniqKey=" As Sikosek N" first="Nina" last=" As Sikošek">Nina As Sikošek</name><affiliation wicri:level="1"><nlm:aff id="j_sjph-2017-0025_aff_002"><institution content-type="university">University Medical Centre Maribor</institution>,<institution content-type="university">University Clinical Department of Gynaecology and Perinatology</institution>,<addr-line>Ljubljanska 5, 2000</addr-line><city>Maribor</city><country country="SI">Slovenia</country></nlm:aff><country xml:lang="fr">Slovénie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Taka, Iztok" sort="Taka, Iztok" uniqKey="Taka I" first="Iztok" last="Taka">Iztok Taka</name><affiliation wicri:level="1"><nlm:aff id="j_sjph-2017-0025_aff_002"><institution content-type="university">University Medical Centre Maribor</institution>,<institution content-type="university">University Clinical Department of Gynaecology and Perinatology</institution>,<addr-line>Ljubljanska 5, 2000</addr-line><city>Maribor</city><country country="SI">Slovenia</country></nlm:aff><country xml:lang="fr">Slovénie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="j_sjph-2017-0025_aff_003"><institution content-type="university">University of Maribor</institution>,<institution content-type="dept">Faculty of Medicine</institution>,<addr-line>Taborska 8, 2000</addr-line><city>Maribor</city><country country="SI">Slovenia</country></nlm:aff><country xml:lang="fr">Slovénie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author></analytic><series><title level="j">Slovenian Journal of Public Health</title><idno type="ISSN">0351-0026</idno><idno type="eISSN">1854-2476</idno><imprint><date when="2017">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><title>Abstract</title><sec id="j_sjph-2017-0025_s_333"><title>Introduction</title><p>Breast cancer is increasingly diagnosed in the early stages without regional nodal involvement. The aim of the present study was to determine the 5-year overall (OS) and breast cancer specific survival (BCSS) for patients with node-negative breast cancer treated at the University Medical Centre Maribor, and compare it with survival at the national level.</p></sec><sec id="j_sjph-2017-0025_s_334"><title>Methods</title><p>Medical records were searched for information on patients with lymph node-negative invasive breast cancer who received primary treatment at the University Medical Centre Maribor in the period 2000–2009. Information on all Slovenian node-negative breast cancer patients diagnosed in the same period was obtained from the Cancer Registry of Republic of Slovenia. Time trends in survival were assessed by comparing the periods 2000–2004 and 2005–2009.</p></sec><sec id="j_sjph-2017-0025_s_335"><title>Results</title><p>The 5-year OS and BCSS of patients treated in Maribor in the period 2000–2009 were 92.3% (95% CI, 90.5%– 94.1%) and 96.4% (95% CI, 95.2%–97.6%), respectively, and did not differ from the corresponding OS and BCSS for Slovenian patients. Although the improvement in OS for patients from Maribor diagnosed in the period 2005–2009 compared to 2000–2004 did not reach statistical significance (HR 0.73; 95% CI, 0.51–1.05; p=0.086), BCSS significantly improved over the same time periods (HR 0.53; 95% CI, 0.30–0.94; p=0.028).</p></sec><sec id="j_sjph-2017-0025_s_336"><title>Conclusions</title><p>Survival of node-negative breast cancer patients treated at the University Medical Centre Maribor is comparable to survival of corresponding patients at the national level. The rising number of long-term breast cancer survivors places additional importance on survivorship care.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Zadnik, V" uniqKey="Zadnik V">V Zadnik</name></author><author><name sortKey="Primic Akelj, M" uniqKey="Primic Akelj M">M Primic Žakelj</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Ferlay, J" uniqKey="Ferlay J">J Ferlay</name></author><author><name sortKey="Steliarova Foucher, E" uniqKey="Steliarova Foucher E">E Steliarova-Foucher</name></author><author><name sortKey="Lortet Tieulent, J" uniqKey="Lortet Tieulent J">J Lortet-Tieulent</name></author><author><name sortKey="Rosso, S" uniqKey="Rosso S">S Rosso</name></author><author><name sortKey="Coebergh, Jw" uniqKey="Coebergh J">JW Coebergh</name></author><author><name sortKey="Comber, H" uniqKey="Comber H">H Comber</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Amaro, J" uniqKey="Amaro J">J Amaro</name></author><author><name sortKey="Severo, M" uniqKey="Severo M">M Severo</name></author><author><name sortKey="Vilela, S" uniqKey="Vilela S">S Vilela</name></author><author><name sortKey="Fonseca, S" uniqKey="Fonseca S">S Fonseca</name></author><author><name sortKey="Fontes, F" uniqKey="Fontes F">F Fontes</name></author><author><name sortKey="La Vecchia, C" uniqKey="La Vecchia C">C La Vecchia</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zadnik, V" uniqKey="Zadnik V">V Zadnik</name></author><author><name sortKey="Zagar, T" uniqKey="Zagar T">T Žagar</name></author><author><name sortKey="Zakelj, Mp" uniqKey="Zakelj M">MP Žakelj</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Altobelli, E" uniqKey="Altobelli E">E Altobelli</name></author><author><name sortKey="Lattanzi, A" uniqKey="Lattanzi A">A Lattanzi</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Myers, Er" uniqKey="Myers E">ER Myers</name></author><author><name sortKey="Moorman, P" uniqKey="Moorman P">P Moorman</name></author><author><name sortKey="Gierisch, Jm" uniqKey="Gierisch J">JM Gierisch</name></author><author><name sortKey="Havrilesky, Lj" uniqKey="Havrilesky L">LJ Havrilesky</name></author><author><name sortKey="Grimm, Lj" uniqKey="Grimm L">LJ Grimm</name></author><author><name sortKey="Ghate, S" uniqKey="Ghate S">S Ghate</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lousdal, Ml" uniqKey="Lousdal M">ML Lousdal</name></author><author><name sortKey="Kristiansen, Is" uniqKey="Kristiansen I">IS Kristiansen</name></author><author><name sortKey="M Ller, B" uniqKey="M Ller B">B Møller</name></author><author><name sortKey="St Vring, H" uniqKey="St Vring H">H Støvring</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Munoz, D" uniqKey="Munoz D">D Munoz</name></author><author><name sortKey="Near, Am" uniqKey="Near A">AM Near</name></author><author><name sortKey="Van Ravesteyn, Nt" uniqKey="Van Ravesteyn N">NT van Ravesteyn</name></author><author><name sortKey="Lee, Sj" uniqKey="Lee S">SJ Lee</name></author><author><name sortKey="Schechter, Cb" uniqKey="Schechter C">CB Schechter</name></author><author><name sortKey="Alagoz, O" uniqKey="Alagoz O">O Alagoz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sant, M" uniqKey="Sant M">M Sant</name></author><author><name sortKey="Chirlaque Lopez, Md" uniqKey="Chirlaque Lopez M">MD Chirlaque Lopez</name></author><author><name sortKey="Agresti, R" uniqKey="Agresti R">R Agresti</name></author><author><name sortKey="Sanchez Perez, Mj" uniqKey="Sanchez Perez M">MJ Sánchez Pérez</name></author><author><name sortKey="Holleczek, B" uniqKey="Holleczek B">B Holleczek</name></author><author><name sortKey="Bielska Lasota, M" uniqKey="Bielska Lasota M">M Bielska-Lasota</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Imkampe, Ak" uniqKey="Imkampe A">AK Imkampe</name></author><author><name sortKey="Bates, T" uniqKey="Bates T">T Bates</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Taib, Na" uniqKey="Taib N">NA Taib</name></author><author><name sortKey="Akmal, M" uniqKey="Akmal M">M Akmal</name></author><author><name sortKey="Mohamed, I" uniqKey="Mohamed I">I Mohamed</name></author><author><name sortKey="Yip, Ch" uniqKey="Yip C">CH Yip</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Darby, S" uniqKey="Darby S">S Darby</name></author><author><name sortKey="Mcgale, P" uniqKey="Mcgale P">P McGale</name></author><author><name sortKey="Correa, C" uniqKey="Correa C">C Correa</name></author><author><name sortKey="Taylor, C" uniqKey="Taylor C">C Taylor</name></author><author><name sortKey="Arriagada, R" uniqKey="Arriagada R">R Arriagada</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Roder, Dm" uniqKey="Roder D">DM Roder</name></author><author><name sortKey="De Silva, P" uniqKey="De Silva P">P de Silva</name></author><author><name sortKey="Zorbas, Hm" uniqKey="Zorbas H">HM Zorbas</name></author><author><name sortKey="Kollias, J" uniqKey="Kollias J">J Kollias</name></author><author><name sortKey="Malycha, Pl" uniqKey="Malycha P">PL Malycha</name></author><author><name sortKey="Pyke, Cm" uniqKey="Pyke C">CM Pyke</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Andersson, Y" uniqKey="Andersson Y">Y Andersson</name></author><author><name sortKey="Frisell, J" uniqKey="Frisell J">J Frisell</name></author><author><name sortKey="Sylvan, M" uniqKey="Sylvan M">M Sylvan</name></author><author><name sortKey="De Boniface, J" uniqKey="De Boniface J">J de Boniface</name></author><author><name sortKey="Bergkvist, L" uniqKey="Bergkvist L">L Bergkvist</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Allemani, C" uniqKey="Allemani C">C Allemani</name></author><author><name sortKey="Sant, M" uniqKey="Sant M">M Sant</name></author><author><name sortKey="Weir, Hk" uniqKey="Weir H">HK Weir</name></author><author><name sortKey="Richardson, Lc" uniqKey="Richardson L">LC Richardson</name></author><author><name sortKey="Baili, P" uniqKey="Baili P">P Baili</name></author><author><name sortKey="Storm, H" uniqKey="Storm H">H Storm</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bodai, Bi" uniqKey="Bodai B">BI Bodai</name></author><author><name sortKey="Tuso, P" uniqKey="Tuso P">P Tuso</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Slovénie</li></country></list><tree><country name="Slovénie"><noRegion><name sortKey="Fokter Dovnik, Nina" sort="Fokter Dovnik, Nina" uniqKey="Fokter Dovnik N" first="Nina" last="Fokter Dovnik">Nina Fokter Dovnik</name></noRegion><name sortKey=" As Sikosek, Nina" sort=" As Sikosek, Nina" uniqKey=" As Sikosek N" first="Nina" last=" As Sikošek">Nina As Sikošek</name><name sortKey="Arko, Darja" sort="Arko, Darja" uniqKey="Arko D" first="Darja" last="Arko">Darja Arko</name><name sortKey="Taka, Iztok" sort="Taka, Iztok" uniqKey="Taka I" first="Iztok" last="Taka">Iztok Taka</name><name sortKey="Taka, Iztok" sort="Taka, Iztok" uniqKey="Taka I" first="Iztok" last="Taka">Iztok Taka</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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